منابع مشابه
Regenerable Thiophenolic Radical-Trapping Antioxidants.
Diphenyl disulfides carrying alkyltelluro groups in the o-, m-, and p-positions were prepared using ortho-lithiation and lithium halogen exchange reactions. The novel antioxidants showed only minimal inhibitory effect on the azo-initiated peroxidation of linoleic acid in chlorobenzene until reduced to the corresponding thiophenols by tris(2-carboxyethyl)phosphine (TCEP). The best in situ genera...
متن کاملTHE DISTURBANCES IN IRON TRANSPORT AND STORES AND TOTAL FREE RADICAL TRAPPING ABILITY OF BLOOD PLASMA IN BABIES WITH MITOCHONDRIAL ENCEPHALO MYOPATHIES
Babies with mitochondrial encephalomyopathies had higher ferritin levels than controls. Although plasma iron levels were simi lar in both groups, babies with mitochondrial encephalomyopathies had lower transferrin levels. Thiobarbituric acid reactive substances in plasma of babies with mitochondrial encephalomyopathies were higher thun in controls suggesting increased lipid oxidation. We s...
متن کاملIdentification of free radical intermediates in oxidized wine using electron paramagnetic resonance spin trapping.
Free radicals are thought to be key intermediates in the oxidation of wine, but their nature has not been established. Electron paramagnetic resonance spectroscopy was used to detect and identify several free radical species in wine under oxidative conditions with the aid of spin traps. The 1-hydroxylethyl radical was the sole radical species observed when α-(4-pyridyl-1-oxide)-N-tert-butylnitr...
متن کاملNmr and Mri Spin Trapping: Using Nmr to Learn about Free Radical Reactions
The paper supports the idea that NMR spectroscopy and imaging can enhance the classical EPR spin trapping techniques. NMR was used to follow and identify the diamagnetic products of DEPMPO/R• spin adduct breakdown. Oxyradical adducts of DEPMPO led to recycling of the spin trap, however, without sufficient long-term accumulation that would enhance EPR detection in vivo. Fluorinated derivative of...
متن کاملThiyl free radical production with hematoporphyrin derivative, cysteine and light: a spin-trapping study.
Hematoporphyrin derivative, used in photodynamic therapy of cancer, was found to generate the cysteinyl free radical as seen by spin-trapping. Oxygen appears to be an absolute requirement for thiyl radical production. Singlet oxygen may be the initiating species since azide inhibits oxygen uptake and radical production. In addition, the hydroxyl radical, or a radical with similar reactivity, is...
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ژورنال
عنوان ژورنال: Nature
سال: 1961
ISSN: 0028-0836,1476-4687
DOI: 10.1038/190478a0